Turmeric is generally recognized as safe by the FDA as a food additive. Serious adverse effects have not been reported in humans ingesting substantial doses of turmeric-curcumin. A dosage escalation trial in twenty-four men and women found that single oral doses as much as 12 gm had been safe and undesirable Curcumin side effects weren’t dose-related.
- In a Phase One trial in Taiwan, Curcumin supplementation of up to 8 gm each day for three months was documented to be well-tolerated in patients with pre-cancerous circumstances or non-invasive cancer.
- In an additional clinical trial within the UK, Curcumin supplementation ranging from 0.45-3.6 gm per day for 4 months was usually well-tolerated by people with advanced colorectal cancer, though two participants experienced mild diarrhoea and another recorded nausea.
Pregnancy and Breast Feeding
Although there is no proof that dietary use of turmeric as a spice negatively affects pregnancy or breast feeding, the safety of Curcumin supplement in pregnancy and lactation hasn’t been established.
Curcumin have a tendency to decelerate blood clotting. If you have bleeding disorders or are under blood thinning medicines, you could experience extreme bleeding even from tiny cuts and bruises. It also increases the probabilities of heavy bleeding during or right after surgery. If you are about to undergo surgery, we highly advise you to quit taking HALTIA Serum supplement a minimum of two weeks before the scheduled surgery.
Turmeric could make the effects of these drugs stronger and raising the threat of bleeding. Blood-thinners contain Warfarin (Coumadin), Clopidogrel (Plavix), and Aspirin, among others.
You will find possibly mild side effects the likes of nausea, upset stomach, and diarrhoea which is mild in nature and would ease off in brief timeframe. If high doses of curcumin supplement are utilized for a lengthened period of time, certain signs of gastrointestinal distress might be experienced.
Curcumin supplementation of 20-40 mg has actually been recorded to improve gall bladder contractions in healthful individuals. Although escalating gallbladder contractions could lower the threat of gallstone formation by encouraging gallbladder draining, it could possibly boost the threat of signs and symptoms in people that currently have gallstones.
Possible Drug Interactions
If you are getting treated with any of the following medications, you need to not use Turmeric or curcumin supplement in medicinal forms without first talking to your health care provider.
- Stomach Acid Medications
The creation of gastric acid might increase when Turmeric is consumed with Cimetidine (Tagamet), Famotidine (Pepcid), Ranitidine (Zantac), Esomeprazole (Nexium), Omeprazole, Lansoprazole (Prevacid).
- Diabetes Medications
Turmeric could make the effects of those drugs stronger, growing the danger of low blood sugar(hypoglycaemia).
- Piperine in Curcumin
You will find several curcumin supplements that include Piperine. Although Piperine is able to improve the bioavailability of Curcumin, it might also reduce the elimination of numerous drugs, including Phenytoin, Propranolol, and Theophylline.