Nano-Curcumin for Gynecological Cancers Treatment

Nano-Curcumin for Gynecological Cancers Treatment

Gynecological cancers are life-threatening and have become significant concern among women. The call to search for a prevention and treatment solutions are particularly demanding as women diagnosed with these cancers are rising, each day! The three forms of Gynecological Cancers are Cervical Cancer, Ovarian Cancer and Uterine Cancer.

Curcumin Anticancer Activity For Gynecological Cancers Treatment

Natural products may offer significant sources as new prospects for cancer cure. Turmeric has been utilized in Ayurvedic treatment and has been researched extensively by scientists throughout the world. An active component identified as Curcumin responsible for fighting various diseases including against cancer cell lines was found with its anticancer activity.

Curcumin for Cervical Cancer Treatment

Cervical cancer or cervical carcinoma is the cancer of the cervix. Cancer may buildup from the surface epithelium of the cervix or from your epithelial lining of the cervical canal and both are invasive. Cervical cancer is regarded as the prevalent cancer particularly in developing countries and it’s often diagnosed in young women. Infection with Human Papillomaviruses (HPVs) results in the progression of this cancer.

In search for the cervical cancer treatment, researchers have reported and established the In-Vitro anticancer activity of curcumin in HPV-associated cells. The effect of curcumin in HPV-associated cells was found to involve the down-regulation of viral oncogenes. In 2010, a study in encapsulation of curcumin in alginate-chitosan-pluronic composite nano-particles against HeLa cells showed promising results. HeLa cells are Human Epithelial Cervical Cancer; the very first human cells from which a permanent cell line was established.

Curcumin for Ovarian Cancer Treatment

Ovarian cancer forms in tissues of the ovary – female reproductive glands in which the ova, or eggs are formed. Most ovarian cancers are either ovarian epithelial carcinoma – cancer that begins in the cells on the surface area of the ovary or malignant germ cell tumors – cancer that begins in egg cells.

Curcumin had remedial effects in ovarian cancer cell lines. Curcumin also had therapeutic and chemosensitization effects and reversed multidrug resistance both in vitro and In-Vivo. Co-administration of curcumin for ovarian cancer treatment and paclitaxel nano-emulsion formulation is effective at overcoming multi-drug resistance in human ovarian adenocarcinoma.

Curcumin for Uterine Cancer Treatment

Uterine Carcinosarcoma is a rare but fast-growing form of uterine cancer that consists of a mix of two types of cancer cells, an uncommon feature of this disease. Surgical procedure to remove the uterus can treat these mixed uterine tumors provided that the condition has not yet spread beyond the uterus. If the condition has spread, it usually does not respond properly to chemo and the outlook for sufferer is undesirable.

A number of research on the anticancer activity of curcumin towards uterine cancer treatment have already been documented regardless of the speculation made in which curcumin may well serve as an effective agent to be utilized in conjunction of chemotherapy for this cancer type. In 2004, it was announced that curcumin demonstrated In-Vitro apoptosis-inducing activity against an endometrial cancer cell line.

Nano-Curcumin for Gynecological Cancers Treatment

The restricting element for Curcumin to be used in Gynecological Cancers Treatment is its low bioavailability and solubility. To be effective, its bioavailability has to be improved. It also needed to be safeguarded from deterioration as a result of metabolic process. This would increase its targeting potential toward cancer cells. Therefore, curcumin with nano-sized particles would able  to deliver an active form of curcumin to tumors.

More clinical studies are needed to explain the actual potential of curcumin and its anticancer activity to fight and prevent Gynecological Cancers.


Anand, P., Sundaram, C., Jhurani, S., Kunnumakkara, A.B., Aggarwal, B.B. (2008).Curcumin and cancer: An “old-age” diseases with and “age-old” solution. Cancer Letters. 267:133-164
Aggarwal, B.B., Bhatt, I.D., Ichikawa, H., Ahn, K.S., Sethi, G., Sandur, S.K., Sundaram, C., Seeram, N., Shishodia, S. (2007).Curcumin- biological and medicinal properties, in: Ravindran, P.N., Babu, K.N., Sivaraman, K. (Eds.). Turmeric the Genus Curcuma. CRC Press, NY. Pp. 297-368.
Das, R.K., Kasoju, N., Bora, U. (2010). Encapsulation of curcumin in alginate-chitosan-pluronic composite nanoparticles for delivery to cancer cells.Nanomedicine. 6:153-160
Divya, C.S., Pillai, M.R. (2006). Antitumor action of curcumin in human papillomavirus associated cells involves downregulation of viral oncogenes, prevention of NFkB and AP-1 translocation and modulation of apoptosis. Mol. Carcinog. 45:320-332
Ganta, S., Amiji, M. (2009).Coadministration of paclitaxel and curcumin in nanoemulsionfromulations to overcome multidrug resistance in tumor cells. Mol. Pharm. 6:928-939 (2012).
Martin, E.A. (2007). Oxford Concise Colour Medical Dictionary.4th Ed. Oxford University Press. United States. p126, 313.
Nair, K.L., Thulasidasan, A.K.T., Deepa, G., Anto, R.J., Vinod Kumar, G.S. (2012). Purely aqueous PLGA nanoparticulate formulations of curcumin exhibit enhanced anticancer activity with dependence on the combination of the carrier. International Journal of Pharmaceutics. 425:44-52
National Cancer Institute(2012)
Sahu, A., Kasoju, N., Bora, U. (2008). Fluorescence study of the curcumin-casein micelle complexation and its application as a drug nanocarrier to cancer cells.Biomacromolecules. 9:2905-2912
Wei, S.C., Lin, Y.S., Tsao, P.N., Wu-Tsai, J.J., Wu, C.H., Wong, J.M. (2004).Comparison of the anti-proliferation and apoptosis-induction activities of sulindac, celecoxib, curcumin and nifedipine in mismatch repair-deficient cell lines. J. Formos. Med. Assoc. 103: 599-606
Yallapu, M.M., Jaggi, M. and Chauhan, S.C. 2012.Curcuminnanoformulations: A future nanomedicine for cancer. Drug Discovery Today. 17: 1/2


MAKNAMajlis Kanser Nasional or MAKNA is a non-profit organisation tasked to gather and harness every effort, expertise and funds to fight cancer, minimize suffering and morbidity cancer sufferers and their families have to endure. MAKNA endeavors to provide curative care, preventive care, cancer research and support services to cancer patients, their loved ones, high-risk groups and the general public. Together with ordinary Malaysians from all parts of society, MAKNA aspire to improve and offer renewed hope to people impacted by cancer.
There is no related post found.
(Visited 146 times, 1 visits today)

, , , , , , , , , , ,


  1. Dingli 123 Did You Know These Organic Treatments For Acne Breakouts? - September 1, 2012

    […] the vast majority of them incorporate chemical plasticizers which have been related to low IQs and Cervical Cancer treatment […]

  2. Arthritis Natural Treatments: An Efficient Different? | - September 3, 2012

    […] cheilitis is horrible. Especially if you happen to be the one which has Gynecological Cancers Treatment. Apart through the aggravating and painful cracks in the corners of your mouth, you can find the […]

  3. Fashion History Costume Trends and Eras, Trends Victorians – Haute Couture» Blog Archive » Natural Cures Superb Cures To Improve Memory And Treatment Social Stress - September 4, 2012

    […] reduction, it may be important to seek the advice of your doctor quickly, particularly when Cervical Cancer treatment discomfort is unbearable. The specific situation might not be substituted by natural solutions and […]

  4. peterten » Get Rid Of Acne Breakouts Scars six Dwelling - September 7, 2012

    […] of these indicators; however, the prescription drugs have downsides. Some have unintended effects anticancer activity major they is usually worse than the indicators their selves. By way of example, several of the […]

  5. What is Green IT Technology? » Blog Archive » Alternative Treatments And Its Advantages - September 10, 2012

    […] of guys suffering of this affliction. There are indeed lots of other items to the current market Gynecological Cancers Treatment promise unbelievable rewards for men with ED, but you can also find people today which have applied […]

  6. The Marketing Blog » Medieval Therapies That Nevertheless Perform Currently - September 14, 2012

    […] demonstrates the assertion that dwelling cures and folk solutions have at least a grain of truth in anticancer activity. Feel about which the up coming time you rub aloe vera juice on a melt away, starve a chilly (or […]

  7. India, Business, Bollywood, Cricket, Video and Breaking News: » Blog Archive » What Not To Do When Taking Arthritis Herbal Solutions - September 15, 2012

    […] proceeds all by their fertility time period. Regardless of a large variety of other causative anticancer activity of irregular menstrual cycle, the necessary elements are fluctuations from the levels of estrogen […]

  8. Eliminate Pimples Scars six Home : Strange collaborations in the Animal Kingdom - November 12, 2012

    […] on the other hand, the prescription prescription drugs have downsides. Some have unintended effects Gynecological Cancers Treatment severe that they may be worse compared to signs themselves. For example, a lot of the prescriptions […]

  9. Curcumin Liver Cancer Treatment – Inhibit Cancer Cells Growth - April 9, 2013

    […] Curcumin has been found to interrupt the cell cycle, have cytotoxic effects and plays a role in anti-proliferation and the induction of a programmed cell death in a hepatocarcinoma – a form of liver cancer cell line. […]

  10. Reality On Bravo » Blog Archive » Cancer: Tips For Making The Most Of Every Day - July 5, 2013

    […] If you have any polyps in your colon, the tobacco will increase their size. These are a few of url the many reasons you need to quit smoking. When you’re depressed, your overall health can […]

  11. Maryannaville » Archiwum Bloga » Androgen deprivation therapy for prostate cancer associated with risk for acute kidney injury - July 23, 2013

    […] prostate cancer. This therapy has traditionally been reserved for patients with advanced disease, nano-curcumin but ADT is increasingly being used in patients with less severe forms of the cancer, such as those […]

  12. Maryannaville » Archiwum Bloga » New study on curcumin for advanced bowel cancer - August 3, 2013

    […] That’s why I had no difficulty in agreeing to take part in the trial. “I’ve met some amazing people since January and my treatment on the NHS has been fantastic. The way I see it […]

  13. Reality On Bravo » Blog Archive » Strategies On How To Lower Your Chances On Getting Cancer - August 5, 2013

    […] beat cancer, finding it early is essential. Be diligent with screening tests so that you breast cancer treatment can detect any problems before symptoms appear. Learn how to perform self-exams for breast or […]

  14. Alarming News » Blog Archive » Holidaying in Turkey - August 10, 2013

    […] supp board yourself. Holidaying in Turkey on 7/8/2013, 7:41:20 86.12.136.x Well we usually play is reference safe by going to Spain every year, but this year we’ve been brave and booked Turkey – now […]

  15. Maryannaville » Archiwum Bloga » Tips For Helping You Deal With Cancer - August 18, 2013

    […] cure. Make sure that you make appointments regularly for screenings and tests that can detect the curcumin for colorectal cancer treatment presence of cancer cells before symptoms begin to show. You can also do regular at home exams on […]

  16. Maryannaville » Archiwum Bloga » Tricks And Tips On How To Lower Your Chances On Getting Cancer - August 21, 2013

    […] curcumin Cervical Cancer Treatment Workouts Will Keep Your Blood Moving Through All Areas Of Your […]

  17. Maryannaville » Archiwum Bloga » What To Do When Diagnosed With Cancer - August 23, 2013

    […] types of contamination. Before eating these nutritious foods, be sure to wash off any pesticide residue. You can do this with a mild detergent and warm water. You may also want to buy organic […]

  18. Breast Cancer Survival Rates Much Lower For Black Women, Regardless Of Type: Study | Small Dead Animals - September 7, 2013

    […] new day for women’s health and the fight against breast cancer.” According to Sebelius, curcumin cervical cancer treatment the healthcare law “means that women can get the potentially life-saving services they need […]

  19. Reality On Bravo » Blog Archive » Tips To Avoid Having Cancer - October 31, 2013

    […] clearly. Sometimes you may choose to answer difficult questions so that others can understand what you’re going through, while other times you may need to set limits on what you will talk […]

  20. Our Gaggle Of Girls : A Successful Cancer Plan To Fight The Disease - November 4, 2013

    […] of various types of cancer to detect it early, like colon cancer. Early indications can include Majlis Kanser Kebangsaan Malaysia unexplained fluctuations in your weight, bloody or thin stools and abdominal cramps. Be sure to get […]

  21. Reality On Bravo » Blog Archive » Simple Tips To Follow When You Have Cancer - November 6, 2013

    […] dealing with cancer, whether it is you or a loved one that is suffering, it is important to be as knowledgeable as possible by reading up on it. Being confident plays a major role in fighting […]

  22. Reality On Bravo » Blog Archive » Advice And Tips To Help You Deal With Cancer - November 13, 2013

    […] be (visit site) afraid if you have to have a screening for breast cancer. The discomfort lasts for only a few […]

  23. Alarming News » Blog Archive » Married Cancer Research Couple Both Get Breast Cancer - December 2, 2013

    […] met a couple who have developed the same kind of breast cancer at the same age. Oliver, 46 years stage 2 breast cancer old, is now undergoing chemotherapy and is looking ahead to his own radical mastectomy in March. […]

  24. Curcumin For Cancer: Part Two | Her Bad Mother - December 16, 2013

    […] The peak blood concentration of curcumin in this study averaged 1.35 micrograms/mL and the enhancer curcumin health benefits substance increased that to 1.80 micrograms/mL. (The precise numbers and other pharmacokinetic data […]

  25. Alarming News » Blog Archive » Cancer Death Rates Drop 29 Percent Over Decade - December 17, 2013

    […] 2001 to 2010, lung cancer deaths dropped 29 percent, a cervical cancer treatment faster rate than in previous years. But Dr. Dan Raz, co-director of City of Hope Lung Cancer […]

  26. Alternative Treatments For Breast Cancer | Small Dead Animals - December 23, 2013

    […] treatment for breast cancer […]

  27. Speedy Solutions In New Breast Cancer Treatment – The Options | Design Mom - December 25, 2013

    […] female role of submissive member of family has to do stage 3 breast cancer a lot with it, the cancer before it has had time to spread anywhere else in the body Cancer is one […]

  28. Men Struggle With Wives’ Breast Cancer In Silence | Small Dead Animals - December 26, 2013

    […] width='250px' cancer treatment style=’float:left;padding:5px’ […]

  29. Breast Cancer Survivors Are Making An Impact | Small Dead Animals - December 28, 2013

    […] After the biopsy, her doctor told her husband and children that she didn’t have cancer. At 52 cancer remedy years old, James was told she would be fine, but everything changed a curcumin liver cancer […]

  30. Obamacare Explained (like You’re An Idiot) | Word Scrawl - December 29, 2013

    […] changes are the least of Obamacare’s problems. A big reason Americans have hesitated to sign up for health insurance is they don’t understand it. A survey of more than 12,000 people […]

  31. Pm Lays Foundation Stone Of Punjab Cancer Hospital | TheWayThereBlog - December 30, 2013

    […] the state needed the hospital, Manmohan Singh said in his address. Thanking the prime minister for curcumin breast cancer treatment taking personal interest in sanctioning the project, Chief Minister Parkash Singh Badal said a […]

  32. Alarming News » Blog Archive » ‘one-stop’ Radiation Treatment Might Offer Breast Cancer Care Alternative - January 8, 2014

    […] found that radiation therapy during surgery worked just as well as conventional treatment in reducing a woman’s five-year risk of breast cancer recurrence. Further, they found that […]

  33. Limited Conclusions For Curcumin From A May 2011 Cancer Study | Her Bad Mother - January 9, 2014

    […] a generic medication, it should sell for a lower cost than its competitive chemotherapy drugs. How nanocurumin Curcumin’s FLLL32 may Augment Cisplatin Cancer Treatment In the Michigan study, adding FLLL32 […]

  34. Our Gaggle Of Girls : Curcumin Causes Colon Cancer Cells To Self-destruct - January 9, 2014

    […] from recommending a cheaper, natural therapy that actually works. Maybe turmeric doesn’t pay curcumin health benefits off their student loans and high salaries. More information at […]

  35. Mediterranean Diet May Protect Against Diabetes | Design Mom - January 9, 2014

    […] us your feedback . 11 Users are viewing the Diabetes Forum right now This will search the titles of kunyit supplement the threads in the Diabetes forum Search the Diabetes Forum: For the original version including any […]

  36. Reality On Bravo » Blog Archive » Inside Trouble-free Secrets Of Curcumin Treatment - January 11, 2014

    […] male breast cancer usually implies: Removal of the entire breast known as mastectomy, along with read more the lymph nodes in the axillary […]

  37. Screening Key In Fighting Cervical Cancer - Mrs. Fussypants Guide To Life - January 15, 2014

    […] department does a weekly screening on Mondays (by appointment) and during a clinic from 11 a.m. to 4 p.m. She said the screening is incorporated into the family planning program. Officials say […]

  38. Our Gaggle Of Girls : Post-surgical Tests Might Help Spot Colon Cancer’s Return - January 17, 2014

    […] Haltia Serum homepage colorectal cancer treatment […]

  39. Foundation Medicine And Memorial Sloan-kettering Cancer Center Announce Partnership To Advance Patient Care In Hematologic Cancers - Mrs. Fussypants Guide To Life - January 27, 2014

    […] effort will focus on co-development of a browse new Foundation Medicine molecular diagnostic product designed to match patients with hematologic […]

  40. Reality On Bravo » Blog Archive » Researchers Develop New Compound Known To Reverse Spread Of Malignant Breast Cancer Cells - January 28, 2014

    […] clinical need to identify new drugs to reverse, or at least to slow down, disease progression he front page added.Dr. Clarksons team joined researchers Dr. Andrea Brancale and Dr. Andrew Westwell, from the […]

  41. Reality On Bravo » Blog Archive » John Theurer Cancer Center Hosts Hematologic Malignancies Program For Physicians And Patients - February 2, 2014

    […] Medicine and Memorial Sloan-Kettering Cancer liver cancer treatment Center Announce Partnership to Advance Patient Care in Hematologic […]

  42. Bounce Back With A Therapy-ball Spine Massage | Martini’s Persistence & A Smile - June 4, 2014

    […] Rx Series at Equinox gyms. Give it a try at home the next time you’re feeling tight.Fitness instructor Jill Miller developed this upper-back soothing massage called the rib rock for the Rx […]

Leave a Reply