Natural Curcumin Extract Outperforms Synthetic Parkinson’s Drugs
Parkinson is a neurodegenerative disease caused by a depletion of dopamine-producing nerve cells, particularly in the area of your brain referred to as the substantia nigra. Most of the current drug treatments for , known as dopamine agonists, focus on replenishing dopamine. Although such treatments provide symptomatic relief during early Parkinson’s disease, they are ineffective in the long term. In fact, in many cases they have actually increased symptoms such as tremor, postural instability and cognitive deficits that are common with this disease. Traditional synthetic drugs for Parkinson are also associated with motor complications, and a laundry list of other strange and disturbing side effects. Not good, and curcumin supplementation carries none of this risk.
Unlike Parkinson’s drugs, curcumin is neuroprotective, and several studies strongly support its use for the treatment of Parkinson. For example, curcumin showed neuroprotective properties in an animal model of Parkinson’s disease. The beneficial effect was thought to be related to its antioxidant capabilities and the ability to easily penetrate the brain. Curcumin alleviated the effects of glutathione depletion, which causes oxidative stress, mitochondria dysfunction and cell death and is a known feature of early Parkinson’s disease. The c-Jun N-terminal kinase (JNK) signaling pathway is involved in dopaminergic neuronal degeneration, which is in turn associated with Parkinson. Curcumin prevents dopaminergic neuronal death through inhibition of the JNK pathway, and thereby offers a neuroprotective effect that may be beneficial for Parkinsons. And finally, its important to note that slow-wriggling alpha-synuclein proteins can cause clumping, which is the first step for diseases such as Parkinson. Curcumin helps prevent these proteins from clumping.
Curcumin Is a Powerful Ally for Your Brain Health
Turmeric, and its active ingredient curcumin, have shown powerful benefits for brain health over many years.and again without side effects associated with traditional drugs. In a similar fashion as vitamin D, it works to modulate large numbers of your genes. In fact, curcumin has been shown to influence more than 700 genes in all. The potential healing power of this spice has been an important part of Eastern cultural traditions, including traditional Chinese medicine and Ayurveda. It first came about when it was noticed that the prevalence of Alzheimer’s disease among older adults in India was more than four times lower than the rate in the United States. Some researchers believe the answer for this drastic difference in Alzheimer’s disease rates is a direct result of curcumin in their regular dietary intake. Subsequently, thorough research has shown that curcumin helps inhibit the accumulation of harmful beta amyloids in the brains of patients. It has also shown significant promise in breaking up existing plaques. People with Alzheimers are also known to exhibit higher levels of inflammation in their brains, and curcumin is perhaps most known for its extremely powerful anti-inflammatory benefits. And finally, curcumin is known to inhibit both the activity and the inflammatory metabolic byproducts of cyclooxygenase-2 (COX2) and 5-lipooxygenase (5-LOX) enzymes, as well as other enzymes and hormones that modulate inflammation.
Vitamin D and omega-3 fats are also powerful preventatives for your overall health, and particularly regarding Parkinson’s and Alzheimer’s diseases. Animal-based omega-3 fats, such as from krill and other fish oils, are a particularly helpful choice, as they contain two fatty acids crucial to human health, DHA and EPA.
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